PUBLICATION
Zebrafish as a model system for studying neuronal circuits and behavior
- Authors
- Fetcho, J.R. and Liu, K.S.
- ID
- ZDB-PUB-990302-48
- Date
- 1998
- Source
- Annals of the New York Academy of Sciences 860: 333-345 (Review)
- Registered Authors
- Fetcho, Joseph R., Liu, Katharine S.
- Keywords
- Animal; Behavior, Animal; Models, Neurological; Neurons; Support, Non-U.S. Gov't; Support, U.S. Gov't, P.H.S.; Zebrafish
- MeSH Terms
-
- Animals
- Behavior, Animal/physiology*
- Models, Neurological*
- Neurons/physiology*
- Zebrafish/physiology*
- PubMed
- 9928323 Full text @ Ann N Y Acad Sci
Citation
Fetcho, J.R. and Liu, K.S. (1998) Zebrafish as a model system for studying neuronal circuits and behavior. Annals of the New York Academy of Sciences. 860:333-345.
Abstract
Zebrafish are best known as a model system for studies of the genetics of development. They do, however, also offer many advantages for the study of neuronal circuitry because the larvae are transparent, allowing optical studies of neuronal activity and noninvasive photoablations of individual neurons. The combination of these optical methods with genetics through the use of mutant and transgenic lines of fish should make the zebrafish model a unique and powerful one among vertebrates. Here we review the strengths of the model and the possibilities it offers for studies of the neural basis of behavior.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping