PUBLICATION
Genetics of neural development in zebrafish
- Authors
- Schier, A.F.
- ID
- ZDB-PUB-970327-16
- Date
- 1997
- Source
- Current opinion in neurobiology 7(1): 119-126 (Review)
- Registered Authors
- Schier, Alexander
- Keywords
- none
- MeSH Terms
-
- Animals
- Cloning, Molecular
- Embryonic and Fetal Development/genetics
- Genes
- Mutation
- Nervous System/embryology*
- Zebrafish/embryology*
- Zebrafish/genetics*
- PubMed
- 9039801 Full text @ Curr. Opin. Neurobiol.
Citation
Schier, A.F. (1997) Genetics of neural development in zebrafish. Current opinion in neurobiology. 7(1):119-126.
Abstract
Large-scale mutant screens in zebrafish have led to the identification of more than 50 genes affecting various aspects of neural development and function, including neural induction, anteroposterior and dorsoventral regionalization, axon pathfinding, neuronal differentiation and survival, and behavior. Phenotypic analysis of mutants for some of these genes has already uncovered important genetic and cellular interactions during development. Ongoing molecular analyses promise to further elucidate the mechanisms underlying neural development in vertebrates.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping