PUBLICATION
Lateral specification of cell fate during vertebrate development
- Authors
- Raible, D.W. and Eisen, J.S.
- ID
- ZDB-PUB-961014-917
- Date
- 1995
- Source
- Current opinion in genetics & development 5: 444-449 (Review)
- Registered Authors
- Eisen, Judith S., Raible, David
- Keywords
- none
- MeSH Terms
-
- Animals
- Caenorhabditis elegans/embryology
- Embryonic Induction
- Motor Neurons/cytology
- Nervous System/embryology*
- Neural Crest/cytology
- Neural Crest/embryology
- Zebrafish/embryology*
- PubMed
- 7580135 Full text @ Curr. Opin. Genet. Dev.
Citation
Raible, D.W. and Eisen, J.S. (1995) Lateral specification of cell fate during vertebrate development. Current opinion in genetics & development. 5:444-449.
Abstract
Cells within equivalence groups interact via lateral specification to determine cell fates during development in Caenorhabditis elegans and other invertebrates. Populations of cells within the developing zebrafish have features similar to those of invertebrate equivalence groups. In a simple example, two identified zebrafish motoneurons behave as an equivalence pair in which one cell adopts a primary fate and interactions between the cells assign the other cell to a secondary fate. A more complicated situation exists for two initially equivalent populations of zebrafish neural crest cells. We consider whether mechanisms similar to those involved in fate specification within invertebrate equivalence groups also function furing fate specification in vertebrates.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping