PUBLICATION

A novel alternative splice domain in zebrafish tenascin-C

Authors
Qiao, T., Maddox, B.K., and Erickson, H.P.
ID
ZDB-PUB-961014-897
Date
1995
Source
Gene   156: 307-308 (Journal)
Registered Authors
Qiao, Tong
Keywords
Fibronectin, fibrinogen, extracellular matrix
MeSH Terms
  • Alternative Splicing*
  • Amino Acid Sequence
  • Animals
  • Cell Adhesion Molecules, Neuronal/genetics*
  • DNA, Complementary/genetics
  • Extracellular Matrix Proteins/genetics*
  • Gene Library
  • Molecular Sequence Data
  • Sequence Analysis, DNA
  • Sequence Homology
  • Tenascin
  • Zebrafish/genetics
PubMed
7538963 Full text @ Gene
Abstract
We have identified and sequenced clones from a zebrafish library that correspond to tenascin-C (TN-C). The 2036-bp sequence covers the C-terminal segment of the protein. Comparison of this sequence to TN-C from other vertebrates indicates that our sequence starts in FN-III domain 5, continues with one alternative splice domain, then with FN-III domains 6-8 and, finally, the complete fibrinogen-like domain. The alternative splice domain, designated TNfnQ, is not closely identified to any of the domains in other species, and may represent a novel descendent of the alternative splice-domain precursor.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping