PUBLICATION
An identified motoneuron with variable fates in embryonic zebrafish
- Authors
- Eisen, J.S., Pike, S.H., and Romancier, B.
- ID
- ZDB-PUB-961014-276
- Date
- 1990
- Source
- The Journal of neuroscience : the official journal of the Society for Neuroscience 10: 34-43 (Journal)
- Registered Authors
- Eisen, Judith S.
- Keywords
- none
- MeSH Terms
-
- Cyprinidae/embryology*
- Neural Pathways/physiology
- Muscles/innervation
- Motor Neurons/physiology*
- Animals
- Cell Survival
- Zebrafish/embryology*
- PubMed
- 2299397 Full text @ J. Neurosci.
Citation
Eisen, J.S., Pike, S.H., and Romancier, B. (1990) An identified motoneuron with variable fates in embryonic zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 10:34-43.
Abstract
Every trunk hemisegment of the zebrafish is innervated by 3 identified primary motoneurons whose development can be observed directly in living embryos. In this paper, we describe another identified neuron that is part of this system. Unlike the other primary motoneurons which are present in all trunk hemisegments, this cell is present in slightly less than half of the trunk hemisegments. Additionally, this cell has at least 2 different fates: it may become a primary motoneuron and arborize in an exclusive muscle territory, or it may die during embryonic development. We have named this cell VaP, for variable primary. We show that the presence of VaP does not affect the early development of the other primary motoneurons in the same hemisegment. Moreover, we show that ablation of both VaP and caudal primary does not alter pathfinding by another identified primary motoneuron.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping