PUBLICATION
            Segregation analysis and gene-centromere distances in zebrafish
- Authors
- Streisinger, G., Singer, F., Walker, C., Knauber, D., and Dower, N.
- ID
- ZDB-PUB-961014-1088
- Date
- 1986
- Source
- Genetics 112: 311-319 (Journal)
- Registered Authors
- Streisinger, George, Walker, Charline
- Keywords
- none
- MeSH Terms
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                - Animals
- Fishes/genetics*
- Chromosomes*
- Lod Score
- Recombination, Genetic
- Mutation
- Centromere*
- Genetic Linkage*
- Genetic Markers
- Homozygote
- Pigmentation
 
- PubMed
- 3455686 Full text @ Genetics
            Citation
        
        
            Streisinger, G., Singer, F., Walker, C., Knauber, D., and Dower, N. (1986) Segregation analysis and gene-centromere distances in zebrafish. Genetics. 112:311-319.
        
    
                
                    
                        Abstract
                    
                    
                
                
            
        
        
    
        
            
            
 
    
    
        
    
    
    
        
                The gol-1, gol-2, alb-1 and spa-1 mutations affect pigment pattern in the zebrafish. We show here that these loci are unlinked to each other. In addition, gene-centromere distances were determined for these loci by analysis of half- tetrads obtained by the inhibition of the second meiotic division. The fractions of tetratype (second-division segregation) tetrads range from 0.24 (spa-1) to 0.89 (gol-1). The observation of greater than 0.67 second-division segregation indicates that the zebrafish has high chiasma interference.
            
    
        
        
    
    
    
                
                    
                        Genes / Markers
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Expression
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Phenotype
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Mutations / Transgenics
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Human Disease / Model
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Sequence Targeting Reagents
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Fish
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Orthology
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Engineered Foreign Genes
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Mapping
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    