PUBLICATION
mSphere of Influence: How host genetics impact microbial pathogenesis and treatment of infectious disease
- Authors
- Rosowski, E.E.
- ID
- ZDB-PUB-231215-1
- Date
- 2023
- Source
- mSphere 9(1): e0062923 (Journal)
- Registered Authors
- Rosowski, Emily E.
- Keywords
- Aspergillus, Mycobacterium, host-pathogen interactions, zebrafish
- MeSH Terms
-
- Communicable Diseases*/therapy
- Host-Pathogen Interactions*
- Humans
- PubMed
- 38095416 Full text @ mSphere
Citation
Rosowski, E.E. (2023) mSphere of Influence: How host genetics impact microbial pathogenesis and treatment of infectious disease. mSphere. 9(1):e0062923.
Abstract
Emily Rosowski works in the field of host-pathogen interactions, studying how host innate immune mechanisms control pathogens. In this mSphere of Influence article, she reflects on how "Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections" by D. M. Tobin, F. J. Roca, S. F. Oh, R. McFarland, et al. (Cell 148:434-446, 2012, https://doi.org/10.1016/j.cell.2011.12.023) made an impact on her by investigating how differences in host genetics can affect modes of microbial pathogenesis and inform treatments for infectious disease.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping