PUBLICATION
The Goldfish Genome and Its Utility for Understanding Gene Regulation and Vertebrate Body Morphology
- Authors
- Omori, Y., Burgess, S.M.
- ID
- ZDB-PUB-230906-72
- Date
- 2024
- Source
- Methods in molecular biology (Clifton, N.J.) 2707: 335355335-355 (Chapter)
- Registered Authors
- Burgess, Shawn
- Keywords
- Domestication, GWAS, Phenotypic variety, Whole-genome duplication
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Gene Expression Regulation
- Genomics
- Goldfish*/genetics
- Zebrafish*/genetics
- PubMed
- 37668923 Full text @ Meth. Mol. Biol.
Citation
Omori, Y., Burgess, S.M. (2024) The Goldfish Genome and Its Utility for Understanding Gene Regulation and Vertebrate Body Morphology. Methods in molecular biology (Clifton, N.J.). 2707:335355335-355.
Abstract
Goldfish, widely viewed as an ornamental fish, is a member of Cyprinidae family and has a very long history in research for both genetics and physiology studies. Among Cyprinidae, the chromosomal locations of orthologs and the amino acid sequences are usually highly conserved. Adult goldfish are 1000 times larger than adult zebrafish (who are in the same family of fishes), which can make it easier to perform several types of experiments compared to their zebrafish cousins. Comparing mutant phenotypes in orthologous genes between goldfish and zebrafish can often be very informative and provide a deeper insight into the gene function than studying the gene in either species alone. Comparative genomics and phenotypic comparisons between goldfish and zebrafish will provide new opportunities for understanding the development and evolution of body forms in the vertebrate lineage.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping