PUBLICATION
The role of starter diets in the development of skeletal abnormalities in zebrafish Danio rerio (Hamilton, 1822)
- Authors
- Antinero, A., Printzi, A., Kourkouta, C., Fragkoulis, S., Mazurais, D., Zambonino-Infante, J.L., Koumoundouros, G.
- ID
- ZDB-PUB-230309-32
- Date
- 2023
- Source
- Journal of fish diseases 46(6): 697-705 (Journal)
- Registered Authors
- Koumoundouros, Giorgos
- Keywords
- abnormalities, finfish larvae, lordosis, nutrition, scoliosis, skeleton
- MeSH Terms
-
- Animals
- Diet/veterinary
- Fish Diseases*
- Larva
- Lordosis*
- Reproducibility of Results
- Zebrafish
- PubMed
- 36883327 Full text @ J. Fish Dis.
Citation
Antinero, A., Printzi, A., Kourkouta, C., Fragkoulis, S., Mazurais, D., Zambonino-Infante, J.L., Koumoundouros, G. (2023) The role of starter diets in the development of skeletal abnormalities in zebrafish Danio rerio (Hamilton, 1822). Journal of fish diseases. 46(6):697-705.
Abstract
Fish skeletal development has long been correlated with nutritional factors. Lack of zebrafish nutritional standardization, especially during the early stages, decreases the reproducibility of the conducted research. The present study represents an evaluation of four commercial (A, D, zebrafish specific; B, generic for freshwater larvae; C, specific for marine fish larvae) and one experimental (Ctrl) early diets on zebrafish skeletal development. Skeletal abnormalities rates in the different experimental groups were assessed at the end of the larval period (20 days post-fertilization, dpf) and after a swimming challenge test (SCT, 20-24 dpf). At 20 dpf, results revealed a significant effect of diet on the rate of caudal-peduncle scoliosis and gill-cover abnormalities, which were relatively elevated in B and C groups. SCT results focused on swimming-induced lordosis, which was comparatively elevated in diets C and D (83% ± 7% and 75% ± 10%, respectively, vs. 52% ± 18% in diet A). No significant effects of dry diets were observed on the survival and growth rate of zebrafish. Results are discussed with respect to the deferential diet composition between the groups and the species requirements. A potential nutritional control of haemal lordosis in finfish aquaculture is suggested.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping