PUBLICATION

FELASA-AALAS Recommendations for Monitoring and Reporting of Laboratory Fish Diseases and Health Status, With an Emphasis on Zebrafish (Danio rerio)

Authors
Mocho, J.P., Collymoore, C., Farmer, S.C., Leguay, E., Murray, K.N., Pereira, N.
ID
ZDB-PUB-220506-27
Date
2022
Source
Comparative medicine   72(3): 127-148 (Journal)
Registered Authors
Murray, Katy
Keywords
none
MeSH Terms
  • Animals
  • Fish Diseases*/diagnosis
  • Fish Diseases*/microbiology
  • Health Status
  • Risk Assessment
  • Zebrafish*
PubMed
35513000 Full text @ Comp. Med.
Abstract
The exchange of fish for research may expose an aquatic laboratory to pathogen contamination as incoming fish can introduce bacteria, fungi, parasites, and viruses capable of affecting both experimental results and fish and personnel health and welfare. To develop risk mitigation strategies, FELASA and AALAS established a joint working group to recommend good practices for health monitoring of laboratory fish. The recommendations address all fish species used for research, with a particular focus on zebrafish (Danio rerio). First, the background of the working group and key definitions are provided. Next, fish diseases of high impact are described. Third, recommendations are made for health monitoring of laboratory fishes. The recommendations emphasize the importance of daily observation of the fish and strategies to determine fish colony health status. Finally, report templates are proposed for historical screening data and aquatic facility description to facilitate biohazard risk assessment when exchanging fish.
Genes / Markers
Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes