PUBLICATION
Spherical arena reveals optokinetic response tuning to stimulus location, size, and frequency across entire visual field of larval zebrafish
- Authors
- Dehmelt, F.A., Meier, R., Hinz, J., Yoshimatsu, T., Simacek, C.A., Huang, R., Wang, K., Baden, T., Arrenberg, A.B.
- ID
- ZDB-PUB-210609-7
- Date
- 2021
- Source
- eLIFE 10: (Journal)
- Registered Authors
- Arrenberg, Aristides, Baden, Tom, Dehmelt, Florian, Yoshimatsu, Takeshi
- Keywords
- neuroscience, zebrafish
- MeSH Terms
-
- Animals
- Female
- Humans
- Larva/physiology
- Larva/radiation effects
- Mice
- Mice, Transgenic
- Nystagmus, Optokinetic/physiology*
- Nystagmus, Optokinetic/radiation effects
- Photic Stimulation/methods*
- Retina/physiology*
- Retina/radiation effects
- Visual Fields/physiology*
- Visual Fields/radiation effects
- Zebrafish
- PubMed
- 34100720 Full text @ Elife
Citation
Dehmelt, F.A., Meier, R., Hinz, J., Yoshimatsu, T., Simacek, C.A., Huang, R., Wang, K., Baden, T., Arrenberg, A.B. (2021) Spherical arena reveals optokinetic response tuning to stimulus location, size, and frequency across entire visual field of larval zebrafish. eLIFE. 10:.
Abstract
Many animals have large visual fields, and sensory circuits may sample those regions of visual space most relevant to behaviours such as gaze stabilisation and hunting. Despite this, relatively small displays are often used in vision neuroscience. To sample stimulus locations across most of the visual field, we built a spherical stimulus arena with 14,848 independently controllable LEDs. We measured the optokinetic response gain of immobilised zebrafish larvae to stimuli of different steradian size and visual field locations. We find that the two eyes are less yoked than previously thought and that spatial frequency tuning is similar across visual field positions. However, zebrafish react most strongly to lateral, nearly equatorial stimuli, consistent with previously reported spatial densities of red, green and blue photoreceptors. Upside-down experiments suggest further extra-retinal processing. Our results demonstrate that motion vision circuits in zebrafish are anisotropic, and preferentially monitor areas with putative behavioural relevance.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping