PUBLICATION
Analysis of the potential behavioral impact of methanol when used as a solvent: Dataset from zebrafish (Danio rerio) behavioral research
- Authors
- Hamilton, T.J., Szaszkiewicz, J., Krook, J., Burggren, W.
- ID
- ZDB-PUB-210424-5
- Date
- 2021
- Source
- Data in brief 36: 107018 (Other)
- Registered Authors
- Burggren, Warren, Hamilton, Trevor
- Keywords
- Behavioral neuroscience, Methanol, Novel object approach test, Open field test, Solvents, Vehicles, Zebrafish
- MeSH Terms
- none
- PubMed
- 33889698 Full text @ Data Brief
Citation
Hamilton, T.J., Szaszkiewicz, J., Krook, J., Burggren, W. (2021) Analysis of the potential behavioral impact of methanol when used as a solvent: Dataset from zebrafish (Danio rerio) behavioral research. Data in brief. 36:107018.
Abstract
Toxicants are commonly administered to experimental organisms using solvents as vehicles. One common vehicle for dissolving toxicants is methanol (CH3OH), a solvent which on its own is capable of altering physiology and behavior high concentrations. This dataset describes behavioral results in zebrafish (Danio rerio) individually exposed to methanol (0.25%, 2.5% vol/vol), or control water, for 30 min prior to behavioral testing. Zebrafish were placed into an open field arena to examine locomotion and zone preference, which was recorded and quantified with motion-tracking software (EthoVision XT). Time spent in the outer ("thigmotaxis") zone of the arena is a proxy for increased anxiety-like behavior in zebrafish. Additionally, a novel object was placed into the center of the arena to quantify relative increases in boldness/exploration between the methanol and control groups. There were no differences in time spent in any zone of the arena or distance travelled between either group, in either test.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping