PUBLICATION
Behavioral Signatures of a Developing Neural Code
- Authors
- Avitan, L., Pujic, Z., Mölter, J., McCullough, M., Zhu, S., Sun, B., Myhre, A.E., Goodhill, G.J.
- ID
- ZDB-PUB-200728-22
- Date
- 2020
- Source
- Current biology : CB 30(17): 3352-3363.e5 (Journal)
- Registered Authors
- Pujic, Zac
- Keywords
- behavioral development, calcium imaging, individual differences, mutual information, neural assemblies, neural decoding, neural development, optic tectum, prey capture, zebrafish
- MeSH Terms
-
- Animals
- Behavior, Animal*
- Exploratory Behavior
- Larva/growth & development
- Larva/physiology*
- Neurons/cytology
- Neurons/physiology*
- Predatory Behavior/physiology*
- Superior Colliculi/growth & development
- Superior Colliculi/physiology*
- Visual Pathways/physiology*
- Zebrafish/growth & development
- Zebrafish/physiology*
- PubMed
- 32710821 Full text @ Curr. Biol.
Citation
Avitan, L., Pujic, Z., Mölter, J., McCullough, M., Zhu, S., Sun, B., Myhre, A.E., Goodhill, G.J. (2020) Behavioral Signatures of a Developing Neural Code. Current biology : CB. 30(17):3352-3363.e5.
Abstract
During early life, neural codes must develop to appropriately transform sensory inputs into behavioral outputs. Here, we demonstrate a link between the maturity of neural coding in the visual brain and developmental changes in visually guided behavior. In zebrafish larvae, we show that visually driven hunting behavior improves from 4 to 15 days post-fertilization, becoming faster and more accurate. During the same period, population activity in parts of the optic tectum refines, improving decoding and information transmission for particular spatial positions. Remarkably, individual differences in decoding can predict each fish's hunting success. Together, these results help reveal how the neural codes required for a natural behavior emerge during development.
Errata / Notes
This article is corrected by ZDB-PUB-220906-215 .
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping