PUBLICATION
Probiotics reduce anxiety-related behavior in zebrafish
- Authors
- Valcarce, D.G., Martínez-Vázquez, J.M., Riesco, M.F., Robles, V.
- ID
- ZDB-PUB-200522-4
- Date
- 2020
- Source
- Heliyon 6: e03973 (Journal)
- Registered Authors
- Keywords
- Animal behavior, Anxiety, Behaviour, Biological sciences, Diet, Neuroscience, Probiotics, Swimming pattern, Swimming speed, Veterinary medicine, Zebrafish, Zoology
- MeSH Terms
- none
- PubMed
- 32435716 Full text @ Heliyon
Citation
Valcarce, D.G., Martínez-Vázquez, J.M., Riesco, M.F., Robles, V. (2020) Probiotics reduce anxiety-related behavior in zebrafish. Heliyon. 6:e03973.
Abstract
There is increasing evidence that gut microbiome could have effects on neurological processes and on behavior. In this study we used the novel tank test (NTT) to analyze zebrafish exploring behavior after four months' supplementation with probiotics with probed antioxidant and anti-inflammatory properties. Results showed that prolonged ingestion of Lactobacillus rhamnosus CECT8361 and Bifidobacterium longum CECT7347 significantly alters the swimming pattern and mean swimming speed in the zebrafish model. After treatment, zebrafish strongly reduced their bottom-dwelling geotactic behavior when placed in a new tank, which could be correlated to a lower state of anxiety.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping