PUBLICATION
Zebrafish toxicity assessment of the photocatalysis-biodegradation of diclofenac using composites of TiO2 and activated carbon from Argania spinosa tree nutshells and Pseudomonas aeruginosa
- Authors
- Daou, C., Hamade, A., El Mouchtari, E.M., Rafqah, S., Piram, A., Wong-Wah-Chung, P., Najjar, F.
- ID
- ZDB-PUB-200403-19
- Date
- 2020
- Source
- Environmental science and pollution research international 27(14): 17258-17267 (Journal)
- Registered Authors
- Hamade, Aline
- Keywords
- ACP-TiO2, Biodegradation, Diclofenac, Heterogeneous photocatalysis, Toxicity, Zebrafish
- MeSH Terms
-
- Animals
- Catalysis
- Charcoal
- Diclofenac
- Ecosystem
- Pseudomonas aeruginosa
- Sapotaceae*
- Titanium
- Trees
- Water Pollutants, Chemical/analysis*
- Zebrafish
- PubMed
- 32152859 Full text @ Environ. Sci. Pollut. Res. Int.
Citation
Daou, C., Hamade, A., El Mouchtari, E.M., Rafqah, S., Piram, A., Wong-Wah-Chung, P., Najjar, F. (2020) Zebrafish toxicity assessment of the photocatalysis-biodegradation of diclofenac using composites of TiO2 and activated carbon from Argania spinosa tree nutshells and Pseudomonas aeruginosa. Environmental science and pollution research international. 27(14):17258-17267.
Abstract
The occurrence and persistence of pharmaceutical products (PPs) in the environment have recently been well-documented and are a major concern for public health. Their incidence in aquatic ecosystems is the result of their direct release without any prior treatment or insufficient wastewater treatment. Therefore, an efficient and safe posttreatment process for removing PPs must be developed. In this study, we focused on the ability of photocatalysis or combined photocatalysis and biodegradation to effectively and safely remove diclofenac (DCF) and its by-products from water. The heterogeneous photocatalysis system was based on bio-sourced activated carbon obtained from Argania spinosa tree nutshells and Degussa P25 titanium dioxide (ACP-TiO2), and biodegradation involved Pseudomonas aeruginosa. Toxicity tests were conducted with zebrafish embryos to evaluate the applicability of the treatment processes. The results showed that photocatalytic treatment with 0.1 mg/L of ACP-TiO2 9% for 7.5 h is sufficient to eliminate DCF (50 mg L-1) and its by-products from water. Low levels of malformation (< 20%) were detected in zebrafish embryos treated with photocatalyzed DCF solutions at 1, 5, and 7 mg L-1 after 4 days of exposure. After 3 h of incubation, P. aeruginosa was found to reduce the toxicity of DCF (10 mg L-1) photocatalyzed for 2 and 4 h. Additional studies should be conducted to elucidate the biodegradation mechanism.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping