PUBLICATION
Expression of ghrelin and leptin in the chemosensory system of adult zebrafish
- Authors
- Montalbano, G., Levanti, M., Abbate, F., Laurà, R., Cavallaro, M., Guerrera, M.C., Germanà, A.
- ID
- ZDB-PUB-200125-11
- Date
- 2020
- Source
- Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 229: 151460 (Journal)
- Registered Authors
- Germanà, Antonino, Guerrera, Maria Cristina, Montalbano, Giuseppe
- Keywords
- chemosensory organ, ghrelin, leptin, zebrafish
- MeSH Terms
-
- Animals
- Chemoreceptor Cells/metabolism*
- Female
- Fluorescent Antibody Technique
- Ghrelin/analysis
- Ghrelin/biosynthesis*
- Gills/metabolism
- Immunohistochemistry
- Leptin/analysis
- Leptin/biosynthesis*
- Male
- Receptors, Odorant/metabolism*
- Skin/metabolism
- Taste Buds/metabolism*
- Zebrafish/metabolism*
- PubMed
- 31978567 Full text @ Ann. Anat.
Citation
Montalbano, G., Levanti, M., Abbate, F., Laurà, R., Cavallaro, M., Guerrera, M.C., Germanà, A. (2020) Expression of ghrelin and leptin in the chemosensory system of adult zebrafish. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 229:151460.
Abstract
Numerous data show that the chemosensory system seems to be modulated by changes in the circulating levels of different molecules such as ghrelin, orexin, leptin, NPY, CCK. The chemosensory system of the zebrafish is represented by the taste buds (skin, oral and oropharyngeal), the olfactory rosette and the solitary chemosensorial cells (SCCs). The purpose of our study was to analyze the distribution of two peripheral hormones such as ghrelin and leptin in the chemosensory organs of the zebrafish. Our results demonstrated the presence of immunoreaction for all antibodies used in the zebrafish chemosensory organs even if with different distribution. In particular, IR was observed for ghrelin in the olfactory rosette while IR for leptin was found in the olfactory rosette, in the skin and oropharyngeal taste buds and in the gills. Both these hormones were detected in the intestine, used as a control.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping