PUBLICATION
Novel fluorene-based fluorescent probe with excellent stability for selective detection of SCN- and its applications in paper-based sensing and bioimaging
- Authors
- Yang, T., Zuo, Y., Zhang, Y., Gou, Z., Wang, X., Lin, W.
- ID
- ZDB-PUB-190801-23
- Date
- 2019
- Source
- Journal of materials chemistry. B 7: 4649-4654 (Journal)
- Registered Authors
- Zhang, Yu
- Keywords
- none
- MeSH Terms
-
- Animals
- Fluorenes*/chemistry
- Fluorescent Dyes/chemistry*
- HeLa Cells
- Humans
- Molecular Imaging/methods*
- Paper
- Polymers/chemistry
- Serum Albumin, Bovine
- Solutions/analysis
- Thiocyanates/analysis*
- Zebrafish
- PubMed
- 31364673 Full text @ J Mater Chem B
Citation
Yang, T., Zuo, Y., Zhang, Y., Gou, Z., Wang, X., Lin, W. (2019) Novel fluorene-based fluorescent probe with excellent stability for selective detection of SCN- and its applications in paper-based sensing and bioimaging. Journal of materials chemistry. B. 7:4649-4654.
Abstract
SCN- is one of the most important anions in metabolic processes. However, the investigation of SCN- in living systems is restricted by the lack of stable functional molecular tools. Herein, the first fluorene-based polymer fluorescent probe V1 was synthesized through rational design. Compared with small molecule fluorescent probes, V1 exhibited excellent fluorescence stability in bovine serum albumin (BSA) solution. Furthermore, the V1-based paper sensor was highly selective toward SCN- in aqueous solution. Significantly, these merits of the probe V1 enable the detection of SCN- in different living cell lines and zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping