ZFIN ID: ZDB-PUB-190601-20
The MCL1-specific inhibitor S63845 acts synergistically with venetoclax/ABT-199 to induce apoptosis in T-cell acute lymphoblastic leukemia cells
Li, Z., He, S., Look, A.T.
Date: 2019
Source: Leukemia   33: 262-266 (Other)
Registered Authors: He, Shuning, Li, Zhaodong, Look, A. Thomas
Keywords: none
MeSH Terms:
  • Animals
  • Antineoplastic Combined Chemotherapy Protocols/therapeutic use*
  • Bridged Bicyclo Compounds, Heterocyclic/administration & dosage
  • Drug Synergism*
  • Embryo, Nonmammalian/drug effects
  • Embryo, Nonmammalian/metabolism
  • Embryo, Nonmammalian/pathology*
  • Humans
  • Myeloid Cell Leukemia Sequence 1 Protein/antagonists & inhibitors*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma/metabolism
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology*
  • Pyrimidines/administration & dosage
  • Sulfonamides/administration & dosage
  • T-Lymphocytes/drug effects
  • T-Lymphocytes/metabolism
  • T-Lymphocytes/pathology*
  • Thiophenes/administration & dosage
  • Tumor Cells, Cultured
  • Zebrafish
PubMed: 30008477 Full text @ Leukemia
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