PUBLICATION
A Regeneration Toolkit
- Authors
- Mokalled, M.H., Poss, K.D.
- ID
- ZDB-PUB-181107-11
- Date
- 2018
- Source
- Developmental Cell 47: 267-280 (Other)
- Registered Authors
- Mokalled, Mayssa, Poss, Kenneth D.
- Keywords
- gene editing, lineage tracing, mice, model systems, salamanders, stem cells, tissue regeneration, zebrafish
- MeSH Terms
-
- Animals
- Humans
- Regeneration/genetics*
- Regeneration/physiology*
- Regenerative Medicine
- Wound Healing/physiology
- PubMed
- 30399333 Full text @ Dev. Cell
Citation
Mokalled, M.H., Poss, K.D. (2018) A Regeneration Toolkit. Developmental Cell. 47:267-280.
Abstract
The ability of animals to replace injured body parts has been a subject of fascination for centuries. The emerging importance of regenerative medicine has reinvigorated investigations of innate tissue regeneration, and the development of powerful genetic tools has fueled discoveries into how tissue regeneration occurs. Here, we present an overview of the armamentarium employed to probe regeneration in vertebrates, highlighting areas where further methodology advancement will deepen mechanistic findings.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping