ZFIN ID: ZDB-PUB-170214-221
Intimacy of the niche: perivascular remodeling cuddles incoming HSCs
Sahai-Hernandez, P., Traver, D.
Date: 2015
Source: Cell Stem Cell   16: 109-10 (Review)
Registered Authors: Traver, David
Keywords: none
MeSH Terms:
  • Animals
  • Endothelium/physiology*
  • Hematopoietic Stem Cells/cytology*
  • Zebrafish/embryology*
PubMed: 25658365 Full text @ Cell Stem Cell
ABSTRACT
Stem cells reside in "niches," which provide signaling cues necessary for self-renewal. In a recent issue of Cell, Tamplin et al. (2015) perform live imaging of hematopoietic stem and progenitor cells (HSPCs) and find dynamic remodeling of endothelial cells is triggered upon arrival of HSPCs at the caudal hematopoietic tissue.
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