ZFIN ID: ZDB-PUB-170214-103
From bench to patient: model systems in drug discovery
Breyer, M.D., Look, A.T., Cifra, A.
Date: 2015
Source: Disease models & mechanisms   8: 1171-4 (Other)
Registered Authors: Look, A. Thomas
Keywords: none
MeSH Terms:
  • Animals
  • Disease Models, Animal
  • Drug Discovery*
  • Genetic Engineering
  • Humans
  • Mice
  • Models, Biological*
  • Translational Medical Research*
  • Zebrafish
PubMed: 26438689 Full text @ Dis. Model. Mech.
Model systems, including laboratory animals, microorganisms, and cell- and tissue-based systems, are central to the discovery and development of new and better drugs for the treatment of human disease. In this issue, Disease Models & Mechanisms launches a Special Collection that illustrates the contribution of model systems to drug discovery and optimisation across multiple disease areas. This collection includes reviews, Editorials, interviews with leading scientists with a foot in both academia and industry, and original research articles reporting new and important insights into disease therapeutics. This Editorial provides a summary of the collection's current contents, highlighting the impact of multiple model systems in moving new discoveries from the laboratory bench to the patients' bedsides.