PUBLICATION
Haematopoietic stem cells show their true colours
- Authors
- North, T.E., Goessling, W.
- ID
- ZDB-PUB-161224-8
- Date
- 2016
- Source
- Nature cell biology 19: 10-12 (Review)
- Registered Authors
- Goessling, Wolfram, North, Trista
- Keywords
- Haematopoietic stem cells, Lineage tracking, Mouse, Zebrafish
- MeSH Terms
-
- Animals
- Cell Tracking
- Clone Cells
- Embryo, Nonmammalian/cytology
- Hematopoietic Stem Cells/cytology*
- Homeostasis
- Mice
- Stress, Physiological
- Zebrafish/embryology
- PubMed
- 28008181 Full text @ Nat. Cell Biol.
Citation
North, T.E., Goessling, W. (2016) Haematopoietic stem cells show their true colours. Nature cell biology. 19:10-12.
Abstract
Delineating the behaviour of haematopoietic stem cells (HSCs) in vivo has thus far proven challenging. Two studies in zebrafish and mouse models now track HSCs in vivo using fate mapping with multicolour approaches to provide further insights into clonal events that regulate blood development, HSC function and differentiation during homeostasis and stress conditions.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping