PUBLICATION
Simultaneous Near-Infrared and Two-Photon In Vivo Imaging of H2 O2 Using a Ratiometric Fluorescent Probe based on the Unique Oxidative Rearrangement of Oxonium.
- Authors
- Dong, B., Song, X., Kong, X., Wang, C., Tang, Y., Liu, Y., Lin, W.
- ID
- ZDB-PUB-160823-9
- Date
- 2016
- Source
- Advanced materials (Deerfield Beach, Fla.) 28(39): 8755-8759 (Journal)
- Registered Authors
- Wang, Chao
- Keywords
- fluorescent probes, hydrogen peroxide, near-infrared imaging, oxidative rearrangement of oxonium, two-photon imaging
- MeSH Terms
-
- Animals
- Cell Survival
- Fluorescent Dyes
- Mice
- Oxidative Stress
- Photons*
- PubMed
- 27545434 Full text @ Adv. Mater. Weinheim
Citation
Dong, B., Song, X., Kong, X., Wang, C., Tang, Y., Liu, Y., Lin, W. (2016) Simultaneous Near-Infrared and Two-Photon In Vivo Imaging of H2 O2 Using a Ratiometric Fluorescent Probe based on the Unique Oxidative Rearrangement of Oxonium.. Advanced materials (Deerfield Beach, Fla.). 28(39):8755-8759.
Abstract
A new ratiometric fluorescent H2 O2 probe, benzopyrylium-coumarin (BC), is designed by using an oxonium moiety as the unique H2 O2 response site. The BC probe exhibits an extremely large emission shift of 221 nm in response to H2 O2 , and is successfully applied for the simultaneous near-infrared and two-photon imaging of H2 O2 in living cells, mouse-liver tissues, and zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping