ZFIN ID: ZDB-PUB-160823-9
Simultaneous Near-Infrared and Two-Photon In Vivo Imaging of H2 O2 Using a Ratiometric Fluorescent Probe based on the Unique Oxidative Rearrangement of Oxonium.
Dong, B., Song, X., Kong, X., Wang, C., Tang, Y., Liu, Y., Lin, W.
Date: 2016
Source: Advanced materials (Deerfield Beach, Fla.)   28(39): 8755-8759 (Journal)
Registered Authors: Wang, Chao
Keywords: fluorescent probes, hydrogen peroxide, near-infrared imaging, oxidative rearrangement of oxonium, two-photon imaging
MeSH Terms:
  • Animals
  • Cell Survival
  • Fluorescent Dyes
  • Mice
  • Oxidative Stress
  • Photons*
PubMed: 27545434 Full text @ Adv. Mater. Weinheim
A new ratiometric fluorescent H2 O2 probe, benzopyrylium-coumarin (BC), is designed by using an oxonium moiety as the unique H2 O2 response site. The BC probe exhibits an extremely large emission shift of 221 nm in response to H2 O2 , and is successfully applied for the simultaneous near-infrared and two-photon imaging of H2 O2 in living cells, mouse-liver tissues, and zebrafish.