PUBLICATION
Evolutionary analysis of the jacalin-related lectin family genes in 11 fishes
- Authors
- Cao, J., Lv, Y.
- ID
- ZDB-PUB-160816-22
- Date
- 2016
- Source
- Fish & shellfish immunology 56: 543-53 (Journal)
- Registered Authors
- Keywords
- Evolution, Expression, Fish, Functional divergence, Jacalin-related lectin
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Evolution, Molecular*
- Fish Proteins/chemistry
- Fish Proteins/genetics*
- Fish Proteins/metabolism
- Fishes/genetics*
- Fishes/immunology*
- Fishes/metabolism
- Lectins/chemistry
- Lectins/genetics*
- Lectins/metabolism
- Phylogeny
- Protein Structure, Tertiary
- Sequence Alignment/veterinary
- Synteny
- PubMed
- 27514782 Full text @ Fish Shellfish Immunol.
Citation
Cao, J., Lv, Y. (2016) Evolutionary analysis of the jacalin-related lectin family genes in 11 fishes. Fish & shellfish immunology. 56:543-53.
Abstract
Jacalin-related lectins are a type of carbohydrate-binding proteins, which are distributed across a wide variety of organisms and involved in some important biological processes. The evolution of this gene family in fishes is unknown. Here, 47 putative jacalin genes in 11 fish species were identified and divided into 4 groups through phylogenetic analysis. Conserved gene organization and motif distribution existed in each group, suggesting their functional conservation. Some fishes have eleven jacalin genes, while others have only one or zero gene in their genomes, suggesting dynamic changes in the number of jacalin genes during the evolution of fishes. Intragenic recombination played a key role in the evolution of jacalin genes. Synteny analyses of jacalin genes in some fishes implied conserved and dynamic evolution characteristics of this gene family and related genome segments. Moreover, a few functional divergence sites were identified within each group pairs. Divergent expression profiles of the zebra fish jacalin genes were further investigated in different stresses. The results provided a foundation for exploring the characterization of the jacalin genes in fishes and will offer insights for additional functional studies.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping