|ZFIN ID: ZDB-PUB-160729-15|
Methodologies for Inducing Cardiac Injury and Assaying Regeneration in Adult Zebrafish
Wang, J., Poss, K.D.
|Source:||Methods in molecular biology (Clifton, N.J.) 1451: 225-35 (Chapter)|
|Registered Authors:||Poss, Kenneth D., Wang, Jinhu|
|Keywords:||Ablation, Cardiomyocyte, Heart, Regeneration, Surgery, Zebrafish|
|PubMed:||27464811 Full text @ Meth. Mol. Biol.|
Wang, J., Poss, K.D. (2016) Methodologies for Inducing Cardiac Injury and Assaying Regeneration in Adult Zebrafish. Methods in molecular biology (Clifton, N.J.). 1451:225-35.
ABSTRACTThe zebrafish has emerged as an important model organism for understanding the cellular and molecular mechanisms of tissue regeneration. Adult zebrafish efficiently replace cardiac muscle after partial resection of their ventricle, or after transgenic ablation of cardiomyocytes. Here, we describe methodology for inducing these injuries and assaying indicators of regeneration.
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