ZFIN ID: ZDB-PUB-160618-12
Quantitative methods for studying hemostasis in zebrafish larvae
Rost, M.S., Grzegorski, S.J., Shavit, J.A.
Date: 2016
Source: Methods in cell biology   134: 377-89 (Chapter)
Registered Authors: Grzegorski, Steven, Rost, Megan, Shavit, Jordan
Keywords: Clotting, Coagulation, Fibrinogen, Hematology, Hemostasis, Thrombosis, Zebrafish
MeSH Terms:
  • Animals
  • Blood Coagulation/genetics*
  • Hemostasis/genetics*
  • Humans
  • Larva/genetics
  • Larva/physiology
  • Thrombosis/genetics*
  • Thrombosis/physiopathology
  • Zebrafish/genetics
  • Zebrafish/physiology
PubMed: 27312499 Full text @ Meth. Cell. Biol.
Hemostasis is a coordinated system through which blood is prevented from exiting a closed circulatory system. We have taken advantage of the zebrafish, an emerging model for the study of blood coagulation, and describe three techniques for quantitative analysis of primary and secondary hemostasis. Collectively, these three techniques comprise a toolset to aid in our understanding of hemostasis and pathological clotting.