ZFIN ID: ZDB-PUB-160618-11
Zebrafish kidney development
Drummond, I.A., Davidson, A.J.
Date: 2016
Source: Methods in cell biology   134: 391-429 (Chapter)
Registered Authors: Davidson, Alan, Drummond, Iain
Keywords: Kidney, Nephron, Organogenesis, Pronephros, Regeneration
MeSH Terms:
  • Animals
  • Gene Expression Regulation, Developmental
  • Humans
  • Kidney/growth & development*
  • Nephrons/growth & development
  • Organogenesis/genetics*
  • Pronephros/growth & development
  • Regeneration/genetics*
  • Zebrafish/genetics
  • Zebrafish/growth & development
PubMed: 27312500 Full text @ Meth. Cell. Biol.
ABSTRACT
The kidney of the zebrafish shares many features with other vertebrate kidneys including the human kidney. Similar cell types and shared developmental and patterning mechanisms make the zebrafish pronephros a valuable model for kidney organogenesis. Here we review recent advances in studies of zebrafish pronephric development and provide experimental protocols to analyze kidney cell types and structures, measure nephron function, live image kidney cells in vivo, and probe mechanisms of kidney regeneration after injury.
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