PUBLICATION
Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo
- Authors
- Zhang, W., Liu, W., Li, P., Kang, J., Wang, J., Wang, H., Tang, B.
- ID
- ZDB-PUB-150527-7
- Date
- 2015
- Source
- Chemical communications (Cambridge, England) 51(50): 10150-3 (Other)
- Registered Authors
- Liu, Wei, Wang, Hui, Zhang, Wei
- Keywords
- none
- MeSH Terms
-
- Animals
- Cell Survival
- Fluorescent Dyes/chemistry*
- Hypochlorous Acid/chemistry*
- Hypochlorous Acid/metabolism*
- Intracellular Space/metabolism
- Mice
- Molecular Imaging/methods*
- Photons*
- RAW 264.7 Cells
- Zebrafish
- PubMed
- 26008174 Full text @ Chem. Commun. (Camb.)
Citation
Zhang, W., Liu, W., Li, P., Kang, J., Wang, J., Wang, H., Tang, B. (2015) Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo. Chemical communications (Cambridge, England). 51(50):10150-3.
Abstract
Herein, we have developed a novel reversible two-photon fluorescent probe that is well suited for monitoring HOCl levels selectively and instantaneously. Results showed the reversible and instantaneous responses of the probe towards intracellular HOCl. Moreover, the probe was successfully applied to the imaging of the HOCl levels in zebrafish and mice via two-photon imaging.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping