PUBLICATION
In Vitro and In Vivo Supramolecular Modification of Biomembranes Using a Lipidated Coiled-Coil Motif
- Authors
- Zope, H.R., Versluis, F., Ordas, A., Voskuhl, J., Spaink, H.P., and Kros, A.
- ID
- ZDB-PUB-131218-19
- Date
- 2013
- Source
- Angewandte Chemie (International ed. in English) 52(52): 14247-51 (Journal)
- Registered Authors
- Spaink, Herman P.
- Keywords
- coiled coil, membranes, peptide amphiphiles, self-assembly, supramolecular chemistry
- MeSH Terms
-
- Amino Acid Sequence
- Humans
- Liposomes/chemistry*
- Peptides/chemistry*
- Protein Binding
- Protein Structure, Tertiary
- PubMed
- 24214899 Full text @ Angew. Chem. Int. Ed. Engl.
Citation
Zope, H.R., Versluis, F., Ordas, A., Voskuhl, J., Spaink, H.P., and Kros, A. (2013) In Vitro and In Vivo Supramolecular Modification of Biomembranes Using a Lipidated Coiled-Coil Motif. Angewandte Chemie (International ed. in English). 52(52):14247-51.
Abstract
Superficial appeal: The surface of live cells and zebrafish embryos can be modified by a supramolecular method. A peptide pair that forms a coiled coil at the cell membrane can be used to dock liposomes in in vitro and in vivo environments (see scheme). This tool can be used in biophysical studies of biological processes occurring at membranes.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping