PUBLICATION

Dynamic expression of neurexophilin1 during zebrafish embryonic development

Authors
Thomas-Jinu, S., and Houart, C.
ID
ZDB-PUB-130806-6
Date
2013
Source
Gene expression patterns : GEP   13(8): 395-401 (Journal)
Registered Authors
Houart, Corinne
Keywords
neuroexophilins, synapses, neurexins, epiphysis, zebrafish, interneurons, neurons
MeSH Terms
  • Amino Acid Sequence
  • Animals
  • Brain/cytology
  • Brain/embryology
  • Brain/metabolism
  • Embryonic Development
  • Gene Expression*
  • Gene Expression Regulation, Developmental
  • Glycoproteins/genetics
  • Glycoproteins/metabolism*
  • Interneurons/metabolism
  • Molecular Sequence Data
  • Neuroglia/metabolism
  • Neuropeptides/genetics
  • Neuropeptides/metabolism*
  • Organ Specificity
  • Phylogeny
  • Sequence Homology, Amino Acid
  • Spinal Cord/cytology
  • Spinal Cord/embryology
  • Spinal Cord/metabolism
  • Zebrafish/embryology
  • Zebrafish/metabolism*
  • Zebrafish Proteins/genetics
  • Zebrafish Proteins/metabolism*
PubMed
23880144 Full text @ Gene Expr. Patterns
Abstract

Neurexophilin 1 (Nxph1) is a specific endoligand of α-neurexins that is essential for trans-synaptic activation. Here, we report its dynamic expression during development in zebrafish. Our study revealed an early onset of expression of nxph1. RT-PCR on a series of embryonic stages showed that it is maternally deposited, although only readily detectable by whole mount in situ hybridization by 22 hpf. During embryogenesis and larval stages, the zygotic transcript is expressed dynamically in various clusters of post-mitotic neurons and in glia in the central nervous system.

Genes / Markers
Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes