ZFIN ID: ZDB-PUB-130308-11
Synthesis of LipidGreen2 and its application in lipid and fatty liver imaging
Chun, H.S., Jeon, J.H., Pagire, H.S., Lee, J.H., Chung, H.C., Park, M.J., So, J.H., Ryu, J.H., Kim, C.H., Ahn, J.H., and Bae, M.A.
Date: 2013
Source: Molecular Biosystems   9(4): 630-633 (Journal)
Registered Authors: Chun, Hang-Suk, Kim, Cheol-Hee, So, Ju-Hoon
Keywords: none
MeSH Terms:
  • Animals
  • Cell Line
  • Fatty Liver/diagnosis*
  • Fluorescent Dyes/chemistry
  • Humans
  • Lipids/chemical synthesis
  • Lipids/chemistry*
  • Mice
  • Molecular Imaging*/methods
  • Molecular Probes/chemistry*
  • Zebrafish
PubMed: 23412429 Full text @ Mol. Biosyst.

We have developed LipidGreen2, a second generation small molecule probe for lipid imaging. LipidGreen2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish. We also demonstrate the application of LipidGreen2 for detecting fatty liver.