PUBLICATION
Synthesis of LipidGreen2 and its application in lipid and fatty liver imaging
- Authors
- Chun, H.S., Jeon, J.H., Pagire, H.S., Lee, J.H., Chung, H.C., Park, M.J., So, J.H., Ryu, J.H., Kim, C.H., Ahn, J.H., and Bae, M.A.
- ID
- ZDB-PUB-130308-11
- Date
- 2013
- Source
- Molecular Biosystems 9(4): 630-633 (Journal)
- Registered Authors
- Chun, Hang-Suk, Kim, Cheol-Hee, So, Ju-Hoon
- Keywords
- none
- MeSH Terms
-
- Animals
- Cell Line
- Fatty Liver/diagnosis*
- Fluorescent Dyes/chemistry
- Humans
- Lipids/chemical synthesis
- Lipids/chemistry*
- Mice
- Molecular Imaging*/methods
- Molecular Probes/chemistry*
- Zebrafish
- PubMed
- 23412429 Full text @ Mol. Biosyst.
Citation
Chun, H.S., Jeon, J.H., Pagire, H.S., Lee, J.H., Chung, H.C., Park, M.J., So, J.H., Ryu, J.H., Kim, C.H., Ahn, J.H., and Bae, M.A. (2013) Synthesis of LipidGreen2 and its application in lipid and fatty liver imaging. Molecular Biosystems. 9(4):630-633.
Abstract
We have developed LipidGreen2, a second generation small molecule probe for lipid imaging. LipidGreen2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish. We also demonstrate the application of LipidGreen2 for detecting fatty liver.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping