PUBLICATION

Anesthesia and euthanasia in zebrafish

Authors
Matthews, M., and Varga, Z.M.
ID
ZDB-PUB-130220-16
Date
2012
Source
ILAR journal   53(2): 192-204 (Review)
Registered Authors
Varga, Zoltan M.
Keywords
none
MeSH Terms
  • Anesthetics*
  • Animals
  • Disease Models, Animal
  • Euthanasia*
  • Zebrafish
PubMed
23382350 Full text @ ILAR (Institute for Laboratory Animal Research)
Abstract

Because of the relative ease of embryonic manipulation and observation, the ability to produce a great number of genetic mutations, efficient screening methods, and the continued advance of molecular genetic tools, such as the progress in sequencing and mapping of the zebrafish genome, the use of zebrafish (Danio rerio) as a biomedical model organism continues to expand. However, studies involving zebrafish husbandry and veterinary care struggle to keep pace with scientific progress. This article outlines some of the current, acceptable methods for providing anesthesia and euthanasia and provides some examples of how performance-based approaches can be used to advance the relatively limited number of anesthetic and euthanizing techniques available for zebrafish.

Genes / Markers
Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes