PUBLICATION
Making limbs from fins
- Authors
- Schneider, I., and Shubin, N.H.
- ID
- ZDB-PUB-121220-25
- Date
- 2012
- Source
- Developmental Cell 23(6): 1121-1122 (Review)
- Registered Authors
- Shubin, Neil
- Keywords
- none
- MeSH Terms
- none
- PubMed
- 23237946 Full text @ Dev. Cell
Citation
Schneider, I., and Shubin, N.H. (2012) Making limbs from fins. Developmental Cell. 23(6):1121-1122.
Abstract
Our limbs evolved from fish fins as vertebrates colonized aquatic shallows and land. If we understood the genetics underlying this transition, could we build a limb on a fish? In this issue of Developmental Cell, Freitas et al. (2012) show that boosting Hoxd13 expression can bring zebrafish one step closer to terra firma.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping