Mione, M., and Zon, L.I. (2012) Cancer and inflammation: an aspirin a day keeps the cancer at bay. Current biology : CB. 22(13):R522-525.
Live imaging of the interactions between oncogene-transformed cells and leukocytes in zebrafish reveals that PGE2 promotes the survival and proliferation of cancer cells. Non-steroid anti-inflammatory drugs, like aspirin, are the effective inhibitors of PGE2 production and could be used with other anti-tumor agents in the treatment of cancer.
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