PUBLICATION
Patterning and Development of the Atrioventricular Canal in Zebrafish
- Authors
- Peal, D.S., Lynch, S.N., and Milan, D.J.
- ID
- ZDB-PUB-111011-25
- Date
- 2011
- Source
- Journal of cardiovascular translational research 4(6): 720-6 (Journal)
- Registered Authors
- Milan, David J.
- Keywords
- atrioventricular canal, zebrafish
- MeSH Terms
-
- Animals
- Body Patterning
- Endocardial Cushions/embryology*
- Endocardial Cushions/metabolism
- Gene Expression Regulation, Developmental
- Heart Valves/embryology*
- Heart Valves/metabolism
- Morphogenesis*
- Signal Transduction
- Zebrafish/embryology*
- Zebrafish/genetics
- Zebrafish/metabolism
- PubMed
- 21948390 Full text @ J.Cardiovasc. Transl. Res.
Citation
Peal, D.S., Lynch, S.N., and Milan, D.J. (2011) Patterning and Development of the Atrioventricular Canal in Zebrafish. Journal of cardiovascular translational research. 4(6):720-6.
Abstract
Proper atrioventricular canal (AVC) patterning and subsequent valvulogenesis is a complex process, and defects can result
in disease or early death. The zebrafish Danio rerio has become a useful model system for studying AVC development, and much progress has been made in dissecting out the critical
steps. Here, we review the recent advances in the field and highlight the cellular and molecular changes observed during zebrafish
AVC development.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping