PUBLICATION
Technologies for micromanipulating, imaging, and phenotyping small invertebrates and vertebrates
- Authors
- Yanik, M.F., Rohde, C.B., and Pardo-Martin, C.
- ID
- ZDB-PUB-110719-16
- Date
- 2011
- Source
- Annual Review of Biomedical Engineering 13: 185-217 (Review)
- Registered Authors
- Yanik, Mehmet Faith
- Keywords
- none
- MeSH Terms
-
- Animals
- Caenorhabditis elegans/cytology
- Caenorhabditis elegans/embryology
- Caenorhabditis elegans/physiology
- Flow Cytometry/instrumentation
- High-Throughput Screening Assays/instrumentation
- High-Throughput Screening Assays/methods
- Humans
- Imaging, Three-Dimensional/instrumentation
- Microfluidic Analytical Techniques*
- Microfluidics*/instrumentation
- Microfluidics*/methods
- Micromanipulation*/instrumentation
- Micromanipulation*/methods
- Microscopy, Confocal/instrumentation
- Molecular Imaging/instrumentation*
- Phenotype
- Zebrafish/embryology
- Zebrafish/physiology
- PubMed
- 21756142 Full text @ Annu. Rev. Biomed. Eng.
Citation
Yanik, M.F., Rohde, C.B., and Pardo-Martin, C. (2011) Technologies for micromanipulating, imaging, and phenotyping small invertebrates and vertebrates. Annual Review of Biomedical Engineering. 13:185-217.
Abstract
Small multicellular model organisms such as the invertebrate nematode C. elegans and the vertebrate zebrafish provide unique opportunities for both basic science and pharmaceutical discovery. In recent years, there have been significant breakthroughs in technologies to manipulate and image these organisms for a variety of purposes ranging from behavioral studies of neuronal circuits to high-throughput screening. Here, we review these advancements with a particular focus on the optically transparent model organisms C. elegans and zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping