PUBLICATION
Imaging circuit formation in zebrafish
- Authors
- Nikolaou, N., and Meyer, M.P.
- ID
- ZDB-PUB-110214-31
- Date
- 2012
- Source
- Developmental Neurobiology 72(3): 346-357 (Review)
- Registered Authors
- Meyer, Martin, Nikolaou, Nikolas
- Keywords
- zebrafish, imaging, synapse, dendrite, axon, circuit, plasticity, molecular biology
- MeSH Terms
-
- Animals
- Axons/physiology
- Axons/ultrastructure*
- Dendrites/physiology
- Dendrites/ultrastructure*
- Humans
- Molecular Imaging*/methods
- Nerve Net/cytology*
- Nerve Net/growth & development
- Nerve Net/physiology
- Neuronal Plasticity/physiology
- Zebrafish/anatomy & histology*
- Zebrafish/growth & development
- Zebrafish/physiology
- PubMed
- 21309080 Full text @ Dev. Neurobiol.
Citation
Nikolaou, N., and Meyer, M.P. (2012) Imaging circuit formation in zebrafish. Developmental Neurobiology. 72(3):346-357.
Abstract
The study of nervous system assembly has been greatly facilitated by recent advances in molecular biology and imaging techniques. These approaches are perfectly suited to young transparent zebrafish where they have allowed direct observation of neural circuit assembly in vivo. In this review will highlight a number of key studies that have applied optical and genetic techniques in zebrafish to address questions relating to axonal and dendritic arbour development, synapse assembly and neural plasticity. These experiments have demonstrated novel cellular phenomena and modes of growth that may reflect general principles governing the assembly of neural circuits.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping