PUBLICATION

The dorsal pallium in Zebrafish, Danio rerio (Cyprinidae, Teleostei)

Authors
Mueller, T., Dong, Z., Berberoglu, M.A., and Guo, S.
ID
ZDB-PUB-110119-16
Date
2011
Source
Brain research   1381: 95-105 (Journal)
Registered Authors
Dong, Zhiqiang, Guo, Su, Mueller, Thomas
Keywords
Amygdala, Cortex, Eversion, Evagination, Forebrain, Migration, Ray-finned fish, Teleost
MeSH Terms
  • Animals
  • Cell Movement
  • Immunohistochemistry
  • Neurons/metabolism
  • Olfactory Pathways/anatomy & histology*
  • Olfactory Pathways/metabolism
  • Parvalbumins/metabolism
  • Telencephalon/anatomy & histology*
  • Telencephalon/metabolism
  • Zebrafish/anatomy & histology*
  • Zebrafish/metabolism
PubMed
21219890 Full text @ Brain Res.
Abstract
Zebrafish as a neurogenetic model system depends on the correct neuroanatomical understanding of its brain organization. Here, we address the unresolved question regarding a possible zebrafish homologue of the dorsal pallial division, the region that in mammals gives rise to the isocortex. Analyzing the distributions of nicotine adenine dinucleotide phosphate diphorase (NADPHd) activity and parvalbumin in the anterior zebrafish telencephalon, we show that against previous assumptions the central (Dc) zone possesses its own germinative region in the dorsal proliferative zone. We define the central (Dc) zone as topologically corresponding to the dorsal pallial division of other vertebrates (mammalian isocortex). In addition, we confirm through BrdU-labeling experiments that the posterior (Dp) zone is formed by radial migration and homologous to the mammalian piriform cortex. Based on our results, we propose a new developmental and organizational model of the zebrafish pallium-one which is the result of a complex outward-inward folding.
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping