PUBLICATION
Fishing for age-related visual system mutants: behavioral screening of retinal degeneration genes in zebrafish
- Authors
- Li, L., Li, Y., Chen, D., Shao, J., Li, X., and Xu, C.
- ID
- ZDB-PUB-100322-15
- Date
- 2010
- Source
- Current aging science 3(1): 43-45 (Review)
- Registered Authors
- Li, Lei, Li, Xin, Li, Yuhao
- Keywords
- none
- MeSH Terms
-
- Aging/genetics*
- Animals
- Behavior, Animal/physiology
- Genetic Testing/methods
- Male
- Models, Animal
- Mutation/genetics
- Retinal Degeneration/genetics*
- Retinal Degeneration/physiopathology
- Zebrafish/genetics*
- PubMed
- 20298169 Full text @ Curr. Aging Sci.
Citation
Li, L., Li, Y., Chen, D., Shao, J., Li, X., and Xu, C. (2010) Fishing for age-related visual system mutants: behavioral screening of retinal degeneration genes in zebrafish. Current aging science. 3(1):43-45.
Abstract
The zebrafish (Danio rerio) has recently become a mainstream model system for genetic studies of human diseases, such as neurological degenerative diseases, heart diseases, immuno-system disorders, etc. In this article, we will review some recent findings of the usefulness of zebrafish as a model vertebrate for behavioral screening of mutations in vertebrate visual system, for example, genes involved in age-related retinal degeneration.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping