PUBLICATION
Fishing for the signals that pattern the face
- Authors
- Schilling, T.F., and Le Pabic, P.
- ID
- ZDB-PUB-100119-3
- Date
- 2009
- Source
- Journal of biology 8(11): 101 (Review)
- Registered Authors
- Schilling, Tom
- Keywords
- none
- MeSH Terms
-
- Animals
- Animals, Genetically Modified
- Body Patterning/genetics*
- Body Patterning/physiology*
- Face/anatomy & histology*
- Face/physiology*
- Gene Expression Regulation/physiology*
- Zebrafish/anatomy & histology*
- Zebrafish/growth & development*
- Zebrafish/physiology
- PubMed
- 20067597 Full text @ J. Biol.
Citation
Schilling, T.F., and Le Pabic, P. (2009) Fishing for the signals that pattern the face. Journal of biology. 8(11):101.
Abstract
Zebrafish are a powerful system for studying the early embryonic events that form the skull and face, as a model for human craniofacial birth defects such as cleft palate. Signaling pathways that pattern the pharyngeal arches (which contain skeletal precursors of the palate, as well as jaws and gills) are discussed in light of a recent paper in BMC Developmental Biology on requirements for Hedgehog signaling in craniofacial development. See research article http://www.biomedcentral.com/1471-213X/9/59.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping