ZFIN ID: ZDB-PUB-091204-6
Adult neurogenesis in non-mammalian vertebrates
Chapouton, P., Jagasia, R., and Bally-Cuif, L.
Date: 2007
Source: BioEssays : news and reviews in molecular, cellular and developmental biology   29(8): 745-757 (Review)
Registered Authors: Bally-Cuif, Laure, Chapouton, Prisca
Keywords: none
MeSH Terms:
  • Adult Stem Cells/physiology*
  • Animals
  • Brain/cytology
  • Brain/physiology*
  • Cell Differentiation
  • Cell Proliferation
  • Models, Animal
  • Models, Biological
  • Nerve Regeneration/physiology*
  • Neurons/physiology*
  • Vertebrates
PubMed: 17621643 Full text @ Bioessays
Adult neurogenesis is an exciting and rapidly advancing field of research. It addresses basic biological questions, such as the how and why of de novo neuronal production during adulthood, as well as medically relevant issues, including the potential link between adult neural stem cells and psychiatric disorders, or how stem cell manipulation might be used as a strategy for neuronal replacement. Current research mainly focuses on rodents, but we review here recent examination of non-mammalian vertebrates, which demonstrates that bona fide adult neural stem cells exist in these species. Importantly, especially in teleost fish, these cells can be abundant and located in various brain areas. Hence, non-mammalian vertebrate species provide invaluable comparative material for extracting core mechanisms of adult neural stem cell maintenance and fate.