PUBLICATION
Chemical Constituents from Clematis delavayi var. spinescens
- Authors
- Li, Y., Wang, S.F., Zhao, Y.L., Liu, K.C., Wang, X.M., Yang, Y.P., and Li, X.L.
- ID
- ZDB-PUB-091120-74
- Date
- 2009
- Source
- Molecules 14(11): 4433-4439 (Journal)
- Registered Authors
- Li, Yang
- Keywords
- coumarin, Clematis delavayi var. spinescens, NMR, antiangiogenic effects
- MeSH Terms
-
- Angiogenesis Inhibitors/pharmacology
- Animals
- Clematis/chemistry*
- Coumarins/chemistry*
- Coumarins/pharmacology*
- Molecular Structure
- Nuclear Magnetic Resonance, Biomolecular
- Phthalazines/pharmacology
- Pyridines/pharmacology
- Zebrafish
- PubMed
- 19924077 Full text @ Molecules
Citation
Li, Y., Wang, S.F., Zhao, Y.L., Liu, K.C., Wang, X.M., Yang, Y.P., and Li, X.L. (2009) Chemical Constituents from Clematis delavayi var. spinescens. Molecules. 14(11):4433-4439.
Abstract
A new coumarin, 7-hydroxy-4,6-dimethoxy-5-methylcoumarin (1), was isolated from the aerial parts of Clematis delavayi var. spinescens together with 17 known compounds. Their structures were identified by extensive spectral analysis, especially 2D NMR techniques. Antiangiogenic effects of all compounds were evaluated using a zebrafish model.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping