PUBLICATION
Liver development in zebrafish (Danio rerio)
- Authors
- Tao, T., and Peng, J.
- ID
- ZDB-PUB-090629-9
- Date
- 2009
- Source
- Journal of genetics and genomics = Yi chuan xue bao 36(6): 325-334 (Review)
- Registered Authors
- Peng, Jinrong
- Keywords
- zebrafish, model organism, liver development, endoderm
- MeSH Terms
-
- Animals
- Cell Differentiation
- Humans
- Liver/embryology*
- Liver/metabolism
- Models, Animal
- Zebrafish/embryology*
- Zebrafish/metabolism
- PubMed
- 19539242 Full text @ J. Genet. Genomics
Citation
Tao, T., and Peng, J. (2009) Liver development in zebrafish (Danio rerio). Journal of genetics and genomics = Yi chuan xue bao. 36(6):325-334.
Abstract
Liver is one of the largest internal organs in the body and its importance for metabolism, detoxification and homeostasis has been well established. In this review, we summarized recent progresses in studying liver initiation and development during embryogenesis using zebrafish as a model system. We mainly focused on topics related to the specification of hepatoblasts from endoderm, the formation and growth of liver bud, the differentiation of hepatocytes and bile duct cells from hepatoblasts, and finally the role of mesodermal signals in controlling liver development in zebrafish.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping