PUBLICATION

Development of a transgenic strategy for facilitated modifier mutation screening in Zebrafish

Authors
Camp, E.M.
ID
ZDB-PUB-090603-85
Date
2003
Source
Ph.D. Thesis : 42p (Thesis)
Registered Authors
Camp, Esther
Keywords
none
MeSH Terms
none
PubMed
none
Abstract
The aim of this study was to develop a transgenic strategy for a facilitated modifier mutation screening in zebrafish. This system represents a potentially powerful method that could be used to study the genetic interactions involved in developmental processes in a vertebrate animal. The overall aim of the project has been to create a transgenic strategy whereby a cloned developmental control gene can be abnormally but non-lethally expressed in the paired fins or melanin producing cells of transgenic zebrafish to cause a visible altered phenotype.
Errata / Notes
Thesis (Ph.D.) -- University of Adelaide, School of Molecular and Biomedical Science, Discipline of Genetics
Genes / Markers
Figures
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping