PUBLICATION
Building an asymmetric brain: Development of the zebrafish epithalamus
- Authors
- Snelson, C.D., and Gamse, J.T.
- ID
- ZDB-PUB-081218-28
- Date
- 2009
- Source
- Seminars in cell & developmental biology 20(4): 491-497 (Review)
- Registered Authors
- Gamse, Josh, Snelson, Corey
- Keywords
- Brain Asymmetry, Epithalamus, Parapineal, Review, Zebrafish
- MeSH Terms
-
- Animals
- Brain/embryology*
- Embryonic Development
- Epithalamus/embryology*
- Functional Laterality*
- Zebrafish
- PubMed
- 19084075 Full text @ Sem. Cell Dev. Biol.
Citation
Snelson, C.D., and Gamse, J.T. (2009) Building an asymmetric brain: Development of the zebrafish epithalamus. Seminars in cell & developmental biology. 20(4):491-497.
Abstract
The human brain exhibits notable asymmetries. Little is known about these symmetry deviations, however scientists are beginning to understand them by employing the lateralized zebrafish epithalamus as a model. The zebrafish epithalamus consists of the pineal and parapineal organs and paired habenular nuclei located bilaterally to the pineal complex. While zebrafish pineal and parapineal organs arise from a common population of cells, parapineal cells undergo a separate program that allows them to migrate left of the pineal anlage. Studying the processes that lead to brain laterality in zebrafish will allow a better understanding of how human brain laterality is established.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping