PUBLICATION
Spatiotemporal features of neurogenesis in the retina of medaka, Oryzias latipes
- Authors
- Kitambi, S.S., and Malicki, J.J.
- ID
- ZDB-PUB-081203-17
- Date
- 2008
- Source
- Developmental Dynamics : an official publication of the American Association of Anatomists 237(12): 3870-3881 (Journal)
- Registered Authors
- Kitambi, Satish Srinivas, Malicki, Jarema
- Keywords
- teleost, medaka, retina, mosaic, photoreceptor, opsin, neurogenesis
- MeSH Terms
-
- Animals
- Cell Division
- Larva/cytology
- Larva/growth & development
- Microscopy, Electron, Transmission
- Neurogenesis*
- Oryzias/embryology*
- Oryzias/growth & development*
- Photoreceptor Cells/cytology
- Retina/cytology
- Retina/embryology*
- Retina/growth & development*
- Somites/cytology
- Somites/embryology
- PubMed
- 19035349 Full text @ Dev. Dyn.
Citation
Kitambi, S.S., and Malicki, J.J. (2008) Spatiotemporal features of neurogenesis in the retina of medaka, Oryzias latipes. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(12):3870-3881.
Abstract
The vertebrate retina is very well conserved in evolution. Its structure and functional features are very similar in phyla as different as primates and teleost fish. Here, we describe the spatiotemporal characteristics of neurogenesis in the retina of a teleost, medaka, and compare them with other species, primarily the zebrafish. Several intriguing differences are observed between medaka and zebrafish. For example, photoreceptor differentiation in the medaka retina starts independently in two different areas, and at more advanced stages of differentiation, medaka and zebrafish retinae display obviously different patterns of the photoreceptor cell mosaic. Medaka and zebrafish evolutionary lineages are thought to have separated from each other 110 million years ago, and so the differences between these species are not unexpected, and may be exploited to gain insight into the architecture of developmental pathways. Importantly, this work highlights the benefits of using multiple teleost models in parallel to understand a developmental process.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping