PUBLICATION
Using imaging and genetics in zebrafish to study developing spinal circuits in vivo
- Authors
- McLean, D.L., and Fetcho, J.R.
- ID
- ZDB-PUB-080414-1
- Date
- 2008
- Source
- Developmental Neurobiology 68(6): 817-834 (Review)
- Registered Authors
- Fetcho, Joseph R.
- Keywords
- optical, molecular, neural networks, spinal cord, locomotion, Danio rerio
- MeSH Terms
-
- Animals
- Diagnostic Imaging*
- Genetic Techniques*
- Neural Pathways/physiology*
- Spinal Cord/anatomy & histology*
- Spinal Cord/growth & development*
- Zebrafish
- PubMed
- 18383546 Full text @ Dev. Neurobiol.
Citation
McLean, D.L., and Fetcho, J.R. (2008) Using imaging and genetics in zebrafish to study developing spinal circuits in vivo. Developmental Neurobiology. 68(6):817-834.
Abstract
Imaging and molecular approaches are perfectly suited to young, transparent zebrafish (Danio rerio), where they have allowed novel functional studies of neural circuits and their links to behavior. Here, we review cutting-edge optical and genetic techniques used to dissect neural circuits in vivo and discuss their application to future studies of developing spinal circuits using living zebrafish. We anticipate that these experiments will reveal general principles governing the assembly of neural circuits that control movements.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping