ZFIN ID: ZDB-PUB-071210-15
Transposons as tools for enhancer trap screens in vertebrates
Korzh, V.
Date: 2007
Source: Genome biology   8(1): S8 (Review)
Registered Authors: Korzh, Vladimir
Keywords: none
MeSH Terms:
  • Animals
  • DNA Transposable Elements/genetics*
  • Enhancer Elements, Genetic*
  • Promoter Regions, Genetic
  • Vertebrates/genetics*
  • Zebrafish
PubMed: 18047700 Full text @ Genome Biol.
ABSTRACT
DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the medaka fish derived Tol2, to enhancer trapping in zebrafish, and how this approach compares with others that have a similar objective.
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