PUBLICATION
Transposons as tools for enhancer trap screens in vertebrates
- Authors
- Korzh, V.
- ID
- ZDB-PUB-071210-15
- Date
- 2007
- Source
- Genome biology 8(1): S8 (Review)
- Registered Authors
- Korzh, Vladimir
- Keywords
- none
- MeSH Terms
-
- Animals
- DNA Transposable Elements/genetics*
- Enhancer Elements, Genetic*
- Promoter Regions, Genetic
- Vertebrates/genetics*
- Zebrafish
- PubMed
- 18047700 Full text @ Genome Biol.
Citation
Korzh, V. (2007) Transposons as tools for enhancer trap screens in vertebrates. Genome biology. 8(1):S8.
Abstract
DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the medaka fish derived Tol2, to enhancer trapping in zebrafish, and how this approach compares with others that have a similar objective.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping