PUBLICATION

The Zebrafish Information Network: the zebrafish model organism database provides expanded support for genotypes and phenotypes

Authors
Sprague, J., Bayraktaroglu, L., Bradford, Y., Conlin, T., Dunn, N., Fashena, D., Frazer, K., Haendel, M., Howe, D.G., Knight, J., Mani, P., Moxon, S.A., Pich, C., Ramachandran, S., Schaper, K., Segerdell, E., Shao, X., Singer, A., Song, P., Sprunger, B., Van Slyke, C.E., and Westerfield, M.
ID
ZDB-PUB-071118-30
Date
2008
Source
Nucleic acids research   36: D768-772 (Journal)
Registered Authors
Bradford, Yvonne, Conlin, Tom, Dunn, Nathan, Fashena, David, Frazer, K., Haendel, Melissa A., Howe, Doug, Knight, Jonathan, Mani, Prita, Moxon, Sierra (fka Taylor), Pich, Christian, Ramachandran, Sridhar, Ruzicka, Leyla, Schaper, Kevin, Segerdell, Erik, Shao, Xiang, Singer, Amy, Song, Peiran, Sprague, Judy, Sprunger, Brock, Van Slyke, Ceri E., Westerfield, Monte
Keywords
none
MeSH Terms
  • Animals
  • Databases, Genetic*
  • Genotype
  • Internet
  • Models, Animal
  • Mutation
  • Phenotype*
  • Sequence Alignment
  • Systems Integration
  • User-Computer Interface
  • Zebrafish/anatomy & histology
  • Zebrafish/genetics*
PubMed
17991680 Full text @ Nucleic Acids Res.
Abstract
The Zebrafish Information Network (ZFIN, http://zfin.org), the model organism database for zebrafish, provides the central location for curated zebrafish genetic, genomic and developmental data. Extensive data integration of mutant phenotypes, genes, expression patterns, sequences, genetic markers, morpholinos, map positions, publications and community resources facilitates the use of the zebrafish as a model for studying gene function, development, behavior and disease. Access to ZFIN data is provided via web-based query forms and through bulk data files. ZFIN is the definitive source for zebrafish gene and allele nomenclature, the zebrafish anatomical ontology (AO) and for zebrafish gene ontology (GO) annotations. ZFIN plays an active role in the development of cross-species ontologies such as the phenotypic quality ontology (PATO) and the gene ontology (GO). Recent enhancements to ZFIN include (i) a new home page and navigation bar, (ii) expanded support for genotypes and phenotypes, (iii) comprehensive phenotype annotations based on anatomical, phenotypic quality and gene ontologies, (iv) a BLAST server tightly integrated with the ZFIN database via ZFIN-specific datasets, (v) a global site search and (vi) help with hands-on resources.
Genes / Markers
Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes