The lateral line microcosmos
- Ghysen, A., and Dambly-Chaudière, C.
- Genes & Development 21(17): 2118-2130 (Review)
- Registered Authors
- Dambly-Chaudière, Christine, Ghysen, Alain
- Lateral line, hair cells, zebrafish, cell migration, regeneration, planar cell polarity
- MeSH Terms
- Body Patterning/genetics
- Cell Movement
- Cell Polarity
- Embryonic Development/genetics*
- Gene Expression Regulation, Developmental
- Hair Cells, Auditory/embryology
- Lateral Line System/embryology*
- Lateral Line System/growth & development
- Lateral Line System/physiology
- Models, Biological
- 17785522 Full text @ Genes & Dev.
Ghysen, A., and Dambly-Chaudière, C. (2007) The lateral line microcosmos. Genes & Development. 21(17):2118-2130.
The lateral-line system is a simple sensory system comprising a number of discrete sense organs, the neuromasts, distributed over the body of fish and amphibians in species-specific patterns. Its development involves fundamental biological processes such as long-range cell migration, planar cell polarity, regeneration, and post-embryonic remodeling. These aspects have been extensively studied in amphibians by experimental embryologists, but it is only recently that the genetic bases of this development have been explored in zebrafish. This review discusses progress made over the past few years in this field.
Genes / Markers
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Engineered Foreign Genes